Carnitine metabolism affects the normal functioning of the whole body, and plays a major role in both lipid and glucose metabolism.
L-carnitine deficiency has been observed in inborn errors of metabolism as well as in infertility, pregnancy, intrauterine growth restriction, premature neonates, liver disease, and in xenobiotics (valproate) evoked toxicity.
Extensive preclinical and clinical research studies have confirmed the positive role that L-carnitine treatment can have not only in the conditions mentioned above but also in other disease states like myalgic encephalomyelitis/chronic fatigue syndrome, neurodegenerative conditions, and diabetes.
New recent research is beginning to show that L-carnitine can also modulate gene expression and other critical biological processes in addition to its key role in mitochondrial energy metabolism.
This series of monographs together with slide presentations and educational videos review the most recent scientific and clinical evidence on the beneficial role of L-carnitine in the management of various medical conditions including fertility and reproduction, fatty liver disease, and valproate induced secondary carnitine deficiency.
This section also includes expert interviews which address current challenges in managing endocrine and metabolic disorders with L-carnitine supplementation.
